Originally Posted by Darlal
In general, keep in mind that all upgrades are scored using your current items. That means that if changing trinkets would seriously alter the relative value of stats, the optimal upgrades might change. There are ways for me to suggest overall optimization but they are (a)much better done with a database (if this seems worthwhile I wouldn't be opposed to it), (b) require cyclic arguments, making the sheet very sensitive and especially platform dependent, and (c) make the final results a bit harder to interpret.
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I've actually toyed with the idea of moving away from a spreadsheet format to avoid some of the limitations of the format; I think the ideal tool would have an initial UI akin to the old CTProfiles site, i.e., a full talent calculator and character sheet page where you can enter your gear and talents. It would probably also want to have an option to fetch your current stats and abilities from the Armory. Then, under the hood, it could go through and do all these calculations in painstaking detail, and provide summary pages indexed by more or less anything you wanted to sort by. On the whole, I think it would make a pretty cool tool, and while I'd be happy to code the underlying computations, my GUI programming skills aren't up to the level that would be required for the project. But if anyone wants to work on putting such a thing together, give me a whistle

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In terms of optomization strategy: figuring out what, in the long run, is the highest dps option tends not to be particularly hard; the challenge is figuring out how to get from point A to point B. I generally take an incremental approach and start with my current gear, then add in the largest reasonably obtainable upgrades and see how much this changes things. In general, the answer is "not too much", but there are some effects (Dragonspine Trophy and TSD, notably) that have a huge impact on the value of stats (hit, in this case) that can change the order of things.
However, the general optomization strategy for someone in early 25man content tends to work out to:
1) get Dragonspine Trophy
2) get to the hit cap
3) profit