A few thoughts
I understand that it's a casual team, but what about having the rogue spec differently? Perhaps trying the bleed game with serrated blades? The other thought would be to have the rogue bring a couple of macro'ed weapons with different poisons so that Mind numbing and a layered poison can be applied on the Paladin initially and then swapped out for some sustained damage to the warrior?
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It's certainly possible that bleeds would be more effective on the warrior - the general tactic for opening on a hardened target is putting SnD up, Exposing, and then using Rupture as necessary with the possibility of a KS -> CB Mutilate -> Mutilate burst.
As far as applying poisons to the paladin, I get basically one opportunity - the initial opener. Depending on the paladin and his communication with his partner I can sometimes stay on them long enough to force a bubble(thank god for purge), but once that's happened and they've skipped out of range Hamstring and JoJ pretty much prevents any chance of that happening again. I generally run Wound MH/Crippling OH with an OH weapon with mind-numbing in my bag that I macro in to Shiv if I think it's worth the risk of losing the snare and the damage.
Thanks for the ideas(from everyone, not just Bias) - it'll be interesting to try them out.