Originally Posted by Maeltne

Keep in mind that due to the additional miss chance granted my defence, your 'dodge+miss' rate with defence is going to be about an absolute 2.6% higher than the 'dodge+miss' rate of resilience.

There is no question that option A is better on overall mitigation. About the only change I would make to the Option A setup is to swap the MoT for the Moroes Trinket. I'd also consider the Juggernaut badge neck.