Originally Posted by Praetorian

This isn't Grid-specific, but it mainly involves Grid. I'm pretty sure I've seen discussion of this issue in the past, but I don't know that I've ever seen a conclusive answer.

I use Clique with Grid in order to heal. I have Clique binds like Shift+LeftClick casting LHW, Ctrl+LeftClick casting HW, etc.

At seemingly random points, but more often in PvP than in raids, my Clique setup will get "stuck" and trying to Shift+LeftClick a Grid frame give me a "gray hand" cursor as though it wants me to select the target for my spell, but clicking again on my intended target still won't make the spell actually cast. This only happens when clicking on Grid frames in particular. When this happens I need to mash Esc a couple of times in order to get things back to normal. In the middle of an arena match this is obviously a terrible thing.

Does anyone have any insight into what causes this or how it can be fixed?