Wotlkwiki has most of the profession changes listed
A summarized list:
* Alchemy can use its transmutes to iterate through all epic gems. It's either:
"2 Eternals + 1 epic gem = 1 epic gem of a different color"
"3 number of the same rare gem = 1 epic gem"
Sky Sapphires (rare blue) turn into Majestic Zircons (epic blue), which can be converted into Ametrines (epic orange) or King's Ambers (epic yellow).
Forest Emeralds (rare green) turn into Eyes of Zul (epic green), which can be converted into Cardinal Rubies (epic red)
Twilight Opals (rare purple) turn into Dreadstones (epic purple)
As well, there's a recipe for the Flask of the North, which has been advertised as an arena-usable stat bonus, instead of the Endless Healing/Mana Potions.
* Blacksmithing has 6 new recipes. What's interesting is that one of the recipes uses the
[Corroded Saronite Woundbringer], which is BOP to Blacksmiths. This could indicate that BS is getting some BOP item upgrades, or that you're simply going to have to provide raw mats. The recipes themselves sound like 3 chestpieces and 3 bracers, which are possibly chestpiece and bracer pairs for tanking, healing and DPS, each.
* Cooking has 6 new recipes, which look to be linked to the new world events
* Enchanting has 1 new pre-WOTLK recipe, while the 3 WOTLK ring enchants have been given an 8 item point upgrade to account for epic gems.
* Engineering has had its Pyro-Rockets, Parachute, Nitro Boosts, Arachnoweave and Armor Webbing all upgraded to account for epic gems.
There's also a new recipe for the advertised mechanical-healing (repairing?) item
Belt-Clipped Spynoculars have been changed to Brassbolt Rebreathers, allowing Engineers to breathe underwater. The mote-cloud-tracking functionality of the Spynoculars are supposed to be passed onto the Mote Extractor itself.
* Herbalism has had its Lifeblood ability upgraded, from 2000 healing to 3600 healing. It's also supposed to be off the GCD and scale with maximum health, although this is not apparent from the data-mined tooltip.
* Inscription has had its Master's Inscriptions upgraded to account for epic gems.
* Leatherworking has had its Fur Linings upgraded to account for epic gems. There are also 8 new recipes 4 for chestpieces and 4 for bracers (possibly a matching chest/bracer pair for leather casters, another for leather physical DPS, another pair for mail casters, and a last pair for mail physical DPS).
* Mining has had its Toughness ability upgraded to account for epic gems.
* Skinning has had its Master of Anatomy ability upgraded to account for epic gems.
* Tailoring has had its various Embroideries upgraded to account for epic gems. There are also 4 new recipes, 2 for chestpieces and 2 for bracers (possibly a matching chest/bracer pair for healing, and another pair for DPS)