I use every default key from 1 to =. (= is cleanse poison)

Y and U are trinkets, G switches my offhand depending on what bar I'm on.

I use 4 bars of 1 - =, but I do think that 4 is the easiest key to use. (earth shock/pummel/overpower)

I use all of wasdqe for moving on my shaman though, I always feel like I'm strafing away from alliance rogues. =/

1 -> attack
2 -> judgement
3 -> soc
q -> fol
e -> holy light
t -> illumination
s -> holyshock

mbutton 1 -> hammer of justice
mbutton 2 -> hammer of wrath
shift mbutton 1 -> consecration
shift mbutton 2 -> freedom
shift wheel up -> bandage
shift wheel down -> mount
shift wheelbutton -> divineshield