Clicking is horribly inefficient for pvp as it draws your attention away from the action and to your cursor. I doubt anyone can click separate abilities faster than their fingers can mash a pattern of keys on their keyboard.
I guess clicking will do in a pve environment, as nearly every class is reduced to either stationary combat, or running around, so they're allowed to be lazy. I still don't see clicking being practical for a class requiring reactionary and quick skills (...main/off tanks).
I don't see why people just don't give keybinding a try. There's no harm in improving your play style, it's rather ignorant to sit back and stay comfortable with an inferior play style when you're just a few menu selections away from a much more efficient manner of play.

It's strange because even though I come from a FPS and MMO background, when I started playing WoW.. I did something I never did before.. bound all my skills to the number pad.

I wasn't a clicker.. but I was a keyboard turner for sure for a long time. I would use my left hand strictly for navigating the character.. right hand would always be rested on the numberpad during combat as that is where all my abilities were bound. It served me well enough for a long time.. until people started pointing out how noob is it to keyboard turn.. and that it severely gimps you in pvp.. and we were beginning to get into AQ40 so..

I switched to mouse turning exclusively, and changed all my key bindings to fit around WASD. It took me a while to find a configuration that I was comfortable with, and it takes a few days to get used to a new setup.. but once I got used to it, it was certainly 5 times better.. my skill tripled. Well.. not tripled.. but I wasn't so restricted by keyboard turning anymore.

my bindings now are something like this

WASD - forward, left turn, right turn, back
(Hold right mouse to strafe)

E - SS / (Garrote)
R - BS / (Ambush)
F - Kidney Shot / (Cheap Shot)
G - Evisc / (Sap)
C - Evasion
V - Vanish
Q - Trinket
X - Kick
1 - EA
2 - Rupture
4 - Gouge
5 - Sprint
T - Stealth / Distract
Shift G - CB
Shift R - SnD
Shift B - Blind
Shift Q - 2nd Trinket


I've got some abilities in weird places but it works great for me. I don't even have to think about what button to press for the right ability anymore. I like everything within easy range of my WASD fingers... I have no idea how people bind abilities to 1-= and hit the right ones while they are running around.. maybe that's classes that take their fingers off the movement keys but for me personally I like to always keep a finger or two on or near the forward and turn buttons because I'm always moving a lot in combat.

As a Hunter I can get away with clicking all of my ranged abilities as they pretty much require standing still to perform. The fact that auot-shot stays active while on the run also keeps this viable. (However, I do bind auto-shot toggle on/off to Shift-W. How I went 60 levels and halfway through BWL without it bound, I have no clue - and, yes, I did just admit this. It is easily the most efficient bind I have ever made.)

All my melee abilities, however, are bound since I need the mouse exclusively for maneuvering at that point.

I think it also depends on the class. If I played a melee class, I'm sure I would have most of my abilities bound.

I have around 70 hotbar buttons bound to different keys.

I have always been a keybinder, but for a long time I was a 'WASD' user and I never really considered that there might be something different (e.g. 'ESDF'). Well, I read a couple posts on the O boards (I know, I know, for shame) about 'ESDF' being better, so I tried it. Although at first, I kept trying to go back to what felt "natural" for me, I eventually adapted to ESDF and now it's second nature to me. In fact, I feel much more flexible now that I'm using ESDF, because it gives you access to several more surrounding number and letter keys.

In terms of keybindings, using ESDF gives me easy reach to all of 1-6. I have four action bars: one for the number key row on my keyboard, one each for modifiers of those keys (shift, alt, and control). Commonly-used abilities, especially for PvP, go in the 1-6 slots on those bars, and less commonly-used abilities go in 7-=.

I play three classes: rogue, priest, and shaman. I can't imagine being a clicker for any of those. Even my rogue would be a monstrous pain if I had to click abilities, but the priest especially would be nigh impossible for group healing. I recall that one priest in my guild had problems healing people outside her own raid group for the longest time. I took a wild guess that she was using the F-keys to select a target and clicking on a heal to cast, which turned out to be the case; so instead, I recommended she do what I do, which is to click a target and use a key to cast a heal. Her healing skills improved drastically just by changing that.

(edit) Quick note...I have four action bars with the standard 12 buttons each. On my rogue, about 2/3 of those buttons are used. On my priest, all of the buttons are used. On my shaman, who's only still level 37, only two buttons are still empty.

On my priest, I find I have to click and hotkey. I just don't have flexible enough fingers to keep all the ranks of heals that I need and shield and renew and fade where they are at a split-second access. So I keep the abilities that I would normally break target to use (such as renew or shield) near my ctraid groups and emergency monitor. I think if you really want to be an effective priest in a raid, you make the most of both clicking and hotkeys. Of course, we also don't have to move around for most raid bosses outside of the most difficult enounters. And Gehennas.

Most of my hotkeys are actually tank macros so I can push buttons to change target and I can use my mouse just to hit up rouges or other dps with renews.

What would you need to keybind as a druid?
For raids I use:

qzd to walk, wc to strafe, alt as selfcast, a to autorun (azerty keyboard btw)
² decursive
1 highest rank HT
2 HT4
3 regrowth max rank
4 rejuneveration max rank
5 HT rank 7

sideways mousebutton swiftmend

I could use a keybind for NS I supose, but I can hit that spot on my screen even with my eyes closed

As a PvE/PvP healer (I do a lot of both), I couldn't imagine not having my spells all bound. I have a ton of different hotkeys and I think that binding your keys really improves your reactions. Another important thing is making sure to learn where each spell is on your keyboard and have easy access to it if you need it.

To the Druid poster above me, I would suggest lots of different ranks for corresponding amounts of healing needed. If Druid HoTs are similar to Renew, there is a great benefit in downranking for a 200-300 per tick Rejuv (my Renew rank 3 ticks for around 300 for 81 mana - hard to beat that). I have 2 Heals, 3 Greater Heals, 3 Flash Heals, 2 Renews, and 2 PoHs on my bars. I also try to min/max as much as possible for a healer. I almost always have Inner Fire up and I even have pretty easy access to Elune's Grace rank 1 just in case 10% dodge might save me - you never know. Fade, Decursive, Heal 1, and Renew 3 are by far my easiest accessed spells, as well as probably the most used.

The only things I really click on is potions, which I have considered key binding but I know I'll accidentally pop them. Also, I highly suggest having a key bound to Assist Target - tabbing through targets just to see who they are hitting and popping heals on them often works a lot better than being the EM spammer (which you can also key bind). I rarely use CTRaid Windows, but do for some fights.