Here's my 2.1 UI during Netherwing rep farming:
The usual suspects: PitBull, Omen, Bartender3, IceHUD, FuBar+plugins, NECB, RicoMiniMap, Satrina Buff Frames, Prat, SCT/D ... Other bars (portals, buffs, trade skills, water/food, etc) are either hidden (mouse-over to show) or paged on the main bar and bound to the extra keys on my G15 keyboard.
The reason I have so much in the center is that I just got a nice new 24" screen and having too much stuff in the corners at 1920x1200 gave me sore eyes
