Latest UI:
Out of combat, in raid. Cast bar is above raid frames, Target is above me, pet to the left of me, target of target is above pet. It's basically Ryas' layout that I recreated, just a tad differently since I like the entire bottom center portion to be set aside for healing frames. DogTags are pretty standard, but I do have a debuff listing starting, as that seemed to be the most popular part of my last post. I'm trying to trim the list down as right now there are over 50 debuffs and it's locking my system up. I'll probably wind up uploading it when I get the debuff list straightened out.

For now, here's the addons used:
Suggestions, comments, etc are always welcome via PM.
