Originally Posted by IceBox

Hamstring gives 63 damage for 10 rage (6.3 dmg/rage_pt)

Imp. Heroic Strike gives 208 damage for 12 rage (17.3 dmg/rage_pt)

Let's say that you can spam Hamstring all the time during your rotation

Rotation timings:

0.0 - Bloodthirst_1
1.5 - Whirlwind_1
3.0 - Hamstring_1
4.5 - Hamstring_2
6.0 - Bloodthirst_1
7.5 - Hamstring_3
9.0 - Hamstring_4
10.5 - Whirlwind_2

In a full rotation, from Whirlwind_1 'til Whirlwind_2 you get time for 4 Hamstrings which are 252 pre-mitigation damage when you can use everything without lag and exactly trigger every spell after the global cooldown. (Work kills my brain, just forgot if Hamstring does proc GCD or not)

So if you can assure that you get enough rage to use Bloodthirst_2 and Whirlwind_2 using two Heroic Strikes instead of Hamstrings would give you more damage (2x208 dmg pre-migitation)

Edit2:
Hamstring doesn't affect your swing timer but triggers GCD (?)
Heroic Strike doesn't trigger your GCD but it doesn't give any rage