Originally Posted by rebirth
DND:
-Some say it does not reach Ultraxion, even if the debuff shows on the boss. (Need verification.)
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DnD does not affect flying mobs, Ultraxion, Deathwing on Madness phase 2, Wing Tentacles and Twilight Assault Drakes, being the foremost in my mind.
AMZ:
-Raid Success may sometimes hinge on AMZ. It's a DPS loss, but may have lead to a faster progression kill. I know this is not the focus on your thread, but just quibbling for completeness for the audience. Notable examples are elementium bolt and twilight onslaught.
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AMZ isn't always a dps loss. In the case of bolts, you're generally not in range of anything when you pop AMZ, so that's a moot point. As for Hour of Twilight, unless you can find a way to survive only on external CDs + IBF, then it can be avoided, but it's amuch better idea to use one UH rune on AMZ than lose ~200 potential RP to using AMS.