Originally Posted by Sh4d0wfury
The ICD should be nothing to worry about, though. You can't really have your diseases unsynced, due to how pestilence works, and most of UH dks don't use GoD, so that there will always be one disease unsynced.
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GoD synchronizes durations, not ticks, so it doesn't matter anyways. You can easily test this on the Ebon Hold boss dummy. If you apply BP first and FF afterwards, BP will always tick more than a second before FF, no matter how often you refresh it with GoD (this is of course only true for the primary target).