Originally Posted by lissanna
If you work insect swarm into your rotation, then the insect swarm glyph is worth picking up. If you don't, that glyph slot is probably better used for the innervate glyph if you need the extra regen in long fights.
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Its worth noting the overall raid impact that the Glyph of Insect Swarm causes. Being that I consider my hunter my main, I'll bring up the flip side of this. Insect Swarm and Scorpid Sting have been normalized to -3% chance to hit on target, and do not stack, so its easy to just say "let a hunter put up scorpid" and take the +30% bugs. I can appreciate this.
In TBC, asking the hunter to put up scorpid sting for the hit debuff was not a big deal, in fact it was pretty much essential in any meaningful raid encounter. No hunter rotation used serpent sting in raiding, so scorpid was a loss of a GCD every 20 seconds and nothing else. No problem. I had Scorpid bitch duty on many nights

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However, this is changing significantly in WotLK. It is absolutely huge to a hunter. Asking a hunter to forego Serpent Sting in lieu of Scorpid Sting will now be a rather large hit.
When you take into account
[Glyph of Steady Shot], it means a 10% damage loss to steady shot, the hunter's primary cast. For an MM specced hunter, it eliminates damage caused by consuming serpent sting via Chimera Shot, which is the cornerstone of MM dps now. For Survival, it means an additional 3% damage loss on top of the Glyph loss due to Noxious Stings talent. And for a BM hunter, well . . . you all know we just spam steady shot. Also, we should bear in mind that no Insect Swarm glyph means losing the +30% damage, where Scorpid Sting means losing 100% of the Serpent Sting damage.
Now I'm not saying people shouldn't Glyph Insect Swarm, but I would say you should have a chat about it with your friendly neighborhood hunters and tanks.