The idea behind mind is simple... Everything that you need to look at is in one area right along the bottom of the screen.
Unit Frames: Ag_Unit Frames
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Action Bars: Bartender 4
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Buffs: Elk Buff Bars
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Threat Meter: Omen
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Combat log: Evesdrop
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Cool Downs:Cooldown Timers3
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Timers: Class Timers
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Those are the major addons all of which are very customizable.
The bottom right corner is eaves drop. It is a simple light combat log which I have been using for years. It is easy to read and follow, you can link hits to chat by shit clicking on them ( useful if you're a tank) It also keeps track of your max hits/heals if that is something you like
To the left of Eaves drop is Cooldown Timers3(and also above) It lets me know when the cool downs are closer to coming up, though I am thinking of moving it to the left side closer to what i pay attention to.
Up at the top I have EBB ( Elkano's Buff Bars) I love these because they are much easier to see and time, and I can create a second group for my pet.
I love my unit frames, though I'm not sure about the long target box yet ( just changed that). I also just recently turned on the portraits for the first time in awhile. At this point in time I am only doing 10-mans, Down the left side i have a unit frame for each member of the raid. Right above my unit frame is my pets where the color of the bar changes from green>yellow>red depending on his happiness.
Just above the pet bar to the right is Class timer. It grows upwards and keeps a bar up for my stings, hunter's mark and other debuff. You can also set it to do buffs on you or your pet if you dont' want to set up the buff bars for your pet like I did.
If you have any questions on any of the other addons I have or use, or on customizing them please feel free to let me know!