I been playing with UI mods since I started to raid 25 mans and found the default UI way lackluster to it.
I'm always looking to tweak and improve my own UI, with two mains goals:
1) Easy readable information.
2) Lightweight, low memory, low cpu usage addons.
So I started to digging trough many addons under many categories, to found one I liked. Is not a easy job, because you need to play extensively with options, and pay a visit to many sources to get the addons that cover one feature you want.
I quick found how important is the placement of stuff on your screen, to become easy readable and show the right information when you need. Also your screen need to be clear, sometimes it looks like people just start installing addons and forget to stop and configure them. Seriously, crap all over the screen is ugly, and the giant black bar covering the bottom 1/4 of the screen is pretty terrible.
This is my actual UI:
On this screen I identified all addons I use by name for easy info. Is pretty self explanatory and all of them can be found on
wowinterface
I know its not a perfect job, so id like to receive any suggestions/criticism of how i can improve it.

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Edit: I received a lot of PM's asking about my Ui, so I am going to write down my list of addons I dint put on original screenshot.
Bartender4 Action Bar replacement.
kgPanels Create frames and panels.
PitBull 3 Unit Frames replacement.
Chatter Chat enhancement addon.
Buffalo Customizing buff display
Minimap Button Frame gather up all of your addon minimap buttons.
Chinchilla For Minimap.
ButtonFacade Skins action bar & buffs.
ButtonFacade: Caith skin for ButtonFacade I use.
OmniCC For action bar CD's.
InfoPanel Bottom info. bar
Also, I am using
SharedMedia with
Hal Texture Compilation (See the readme inside zip) for textures and borders.