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With haste being stronger for Demo than Int, will it make sense to replace Int/haste gems with pure haste gems?
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This depends on your specific gear setup, the anwser at high end gear levels is likely yes. However also depends on latency.
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1. what is the best opening cast sequence for affliction ?
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Corr->UA->BoA->Haunt. The reason we previously used a shadow bolt first was solely due to crit rolling. Now that crit rolling is fixed and sp/haste/crit are updated every single time corruption gets refreshed, the extra ticks you'll get from applying dots first will outweigh the benefit of having a % more damage on 1 o2 r ticks, but also 1 or 2 ticks less in total. The reason I put haunt higher on the priority list than UA/BoA is because haunt is also responsible for Shadow Embrace esspecially below 25%), and 3 stacks of shadow embrace falling off and needing tobe re-applied will cost you a ton of damage.
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Also, in the priority list you wrote Shadowflame as a spell, but I believe you meant Shadowburn?
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Nope, Shadowflame. When they removed the horror effect from this in beta they decided to buff it's damage so it wouldnt be totally useless. Unfortunately now it's so powerful that we should use it in our single target DPS rotation.
I actually haven't done any testing or looked at base damage / spellpower co-efficient for shadow burn, I'm not 100% sure if we should be using that or not.
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Last, I have a question for you: Is CoE still not viable, or should we be using it now?
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Since you can now use CoE while also using your damage banes, using CoE is often a good idea.
And yeah- I'll check out glyphs.
PS. Please edit the large quote out of your post.